| Drug General Information |
| Drug ID |
D07NYX
|
| Former ID |
DNC002481
|
| Drug Name |
BENZOTHIAZOLE
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C7H5NS
|
| Canonical SMILES |
C1=CC=C2C(=C1)N=CS2
|
| InChI |
1S/C7H5NS/c1-2-4-7-6(3-1)8-5-9-7/h1-5H
|
| InChIKey |
IOJUPLGTWVMSFF-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
73754, 592933, 609129, 866754, 3134907, 4490391, 7886302, 7890776, 8154813, 10538612, 15363581, 16957271, 17389158, 24420945, 24846538, 24847809, 24901589, 29214970, 29226115, 30974504, 37338128, 37451931, 37466658, 37606085, 38460075, 38460086, 38493745, 42883245, 48420796, 48422933, 48424868, 49835791, 49856076, 51072492, 53788178, 56322737, 57324038, 58097295, 75841476, 80953807, 87563291, 88822835, 92719874, 96022834, 103603559, 104314329, 104668601, 118080824, 124890859, 125360198
|
| Target and Pathway |
| Target(s) |
Coagulation factor IIa |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
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Neuroactive ligand-receptor interaction
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Complement and coagulation cascades
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Regulation of actin cytoskeleton
|
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NetPath Pathway
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TCR Signaling Pathway
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PANTHER Pathway
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Blood coagulation
|
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Pathway Interaction Database
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Thrombin/protease-activated receptor (PAR) pathway
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Angiopoietin receptor Tie2-mediated signaling
|
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FOXA2 and FOXA3 transcription factor networks
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PAR4-mediated thrombin signaling events
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Syndecan-4-mediated signaling events
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PAR1-mediated thrombin signaling events
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PathWhiz Pathway
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Vitamin K Metabolism
|
|
Coagulation
|
|
Reactome
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Intrinsic Pathway of Fibrin Clot Formation
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Common Pathway of Fibrin Clot Formation
|
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Gamma-carboxylation of protein precursors
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Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
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Removal of aminoterminal propeptides from gamma-carboxylated proteins
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Cell surface interactions at the vascular wall
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Peptide ligand-binding receptors
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Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
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G alpha (q) signalling events
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Thrombin signalling through proteinase activated receptors (PARs)
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WikiPathways
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Complement and Coagulation Cascades
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Regulation of Actin Cytoskeleton
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IL1 and megakaryotyces in obesity
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Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
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PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
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Blood Clotting Cascade
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Gastrin-CREB signalling pathway via PKC and MAPK
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Thrombin signalling through proteinase activated receptors (PARs)
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Platelet Aggregation (Plug Formation)
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GPCR ligand binding
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GPCR downstream signaling
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Formation of Fibrin Clot (Clotting Cascade)
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Cell surface interactions at the vascular wall
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Folate Metabolism
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Vitamin B12 Metabolism
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Selenium Micronutrient Network
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| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
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