Drug Information

Drug General Information
Drug ID
D07NTN
Former ID
DIB012718
Drug Name
CERM-11956
Synonyms
N-(1,3-Benzodioxolan-5-yl)-N-phenylmethyl-beta-[(2-methylpropoxy)methyl]-1-pyrrolidinylethanamine fumarate; 2-(N-Pyrrolidino)-3-isobutoxy-N-(3,4-methylenedioxyphenyl)-N-benzylpropylamine fumarate
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Discontinued in Phase 1 [544570]
Structure
Download
2D MOL

3D MOL
Formula
C29H38N2O7
Canonical SMILES
CCC(C)OCC(CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)OCO3)N4CCCC4.C(<br />=CC(=O)O)C(=O)O
InChI
1S/C25H34N2O3.C4H4O4/c1-3-20(2)28-18-23(26-13-7-8-14-26)17-27(16-21-9-5-4-6-10-21)22-11-12-24-25(15-22)30-19-29-24;5-3(6)1-2-4(7)8/h4-6,9-12,15,20,23H,3,7-8,13-14,16-19H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChIKey
RDZJRZMQCVQTSK-WLHGVMLRSA-N
CAS Number
CAS 97631-49-7
PubChem Compound ID
6438764
PubChem Substance ID
43031735, 77535964, 114556903, 135083096
Target and Pathway
Target(s) Calcium channel Target Info Antagonist [533437], [551871]
References
Ref 544570Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000166)
Ref 533437The anti-ischaemic activity of the novel compound, CERM 11956, compared with that of bepridil and nifedipine in isolated guinea-pig hearts. Eur J Pharmacol. 1988 May 10;149(3):195-203.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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