Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D07LCY
|
||||
Former ID |
DIB006342
|
||||
Drug Name |
RVSVIN HIV-1 gag vaccine
|
||||
Synonyms |
RVSVIN HIV-1 gag vaccine, Profectus Biosciences; RVSV vector-based HIV-1 vaccine, Profectus BioSciences; Recombinant VSV vector-based HIV-1 vaccine, Profectus BioSciences; Recombinant vesicular stomatitis virus vector-based HIV-1 vaccine, Profectus BioSciences
|
||||
Drug Type |
Vaccine
|
||||
Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 1 | [549955] | ||
Company |
Wyeth Pharmaceuticals
|
||||
Target and Pathway | |||||
Target(s) | HIV GAG protein | Target Info | [531652] | ||
Reactome | Uncoating of the HIV Virion | ||||
Budding and maturation of HIV virion | |||||
Integration of provirus | |||||
Early Phase of HIV Life Cycle | |||||
Minus-strand DNA synthesis | |||||
Plus-strand DNA synthesis | |||||
2-LTR circle formation | |||||
Binding and entry of HIV virion | |||||
Membrane binding and targetting of GAG proteins | |||||
Assembly Of The HIV Virion | |||||
Integration of viral DNA into host genomic DNA | |||||
Autointegration results in viral DNA circles | |||||
APOBEC3G mediated resistance to HIV-1 infection | |||||
Vpr-mediated nuclear import of PICs | |||||
WikiPathways | Host Interactions of HIV factors | ||||
HIV Life Cycle | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.