Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07JRW
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| Former ID |
DNC009189
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| Drug Name |
Jaspic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C27H38O3
|
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| Canonical SMILES |
CC1=CCC2C(CCCC2(C1CC3=C(C=CC(=C3)C(=O)O)O)C)(C)CCC=C(C)<br />C
|
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| InChI |
1S/C27H38O3/c1-18(2)8-6-13-26(4)14-7-15-27(5)22(19(3)9-12-24(26)27)17-21-16-20(25(29)30)10-11-23(21)28/h8-11,16,22,24,28H,6-7,12-15,17H2,1-5H3,(H,29,30)/t22-,24-,26-,27+/m0/s1
|
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| InChIKey |
IIMZFSAVKIVVHG-DAANFHMWSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 15-lipoxygenase | Target Info | Inhibitor | [1] | |
| Arachidonate 12-lipoxygenase, 12S-type | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Resolvin D biosynthesis | ||||
| Lipoxin biosynthesisPWY66-392:Lipoxin biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Linoleic acid metabolism | |||||
| Metabolic pathways | |||||
| Serotonergic synapsehsa00590:Arachidonic acid metabolism | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathwayP00031:Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| PathWhiz Pathway | Arachidonic Acid MetabolismPW000044:Arachidonic Acid Metabolism | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid SynthesisWP2650:Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | J Nat Prod. 2003 Feb;66(2):230-5.Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. | ||||
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