Drug Information

Drug General Information
Drug ID
D07HYR
Former ID
DIB015139
Drug Name
GCC-1290K
Synonyms
GC-1290K; GC-2101; GCC-1290A; GCC-1290K (salt formulation, oral), Green Cross; Dopamine modulators (Parkinson's disease, oral), Kangwon University/Green Cross; (+)-3-hydroxymorphinan; 3-HM; 3-HM prodrugs (Parkinson's disease), Green Cross; 3-hydroxymorphinan prodrugs (Parkinson's disease), Green Cross
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Phase 1 [530122]
Company
Kangwon University Pharmaceutical College
Structure
Download
2D MOL

3D MOL
Canonical SMILES
[C@]123c4cc(ccc4C[C@@H]([C@H]1CCCC2)NCC3)OCOC(=O)OC(C)C<br />.OC(=O)[C@@H]([C@H](C(=O)O)O)O.O
Target and Pathway
Target(s) Voltage-dependent calcium channel Target Info Modulator [530122]
Protein kinase C Target Info Modulator [530122]
References
Ref 530122Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan. Neurochem Int. 2009 Jul;54(8):526-34.
Ref 530122Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan. Neurochem Int. 2009 Jul;54(8):526-34.

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