Drug General Information
Drug ID
D07FRX
Former ID
DNC014631
Drug Name
6-Thiophen-3-yl-imidazo[2,1-b]thiazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533704]
Structure
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2D MOL

3D MOL

Formula
C9H6N2S2
Canonical SMILES
C1=CSC=C1C2=CN3C=CSC3=N2
InChI
1S/C9H6N2S2/c1-3-12-6-7(1)8-5-11-2-4-13-9(11)10-8/h1-6H
InChIKey
QNYBFCDYFVERKH-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) NADH dehydrogenase Target Info Inhibitor [533704]
KEGG Pathway Oxidative phosphorylation
Metabolic pathways
Parkinson's disease
WikiPathways Oxidative phosphorylation
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Electron Transport Chain
References
Ref 533704J Med Chem. 1995 Mar 31;38(7):1090-7.Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase.
Ref 533704J Med Chem. 1995 Mar 31;38(7):1090-7.Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase.

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