Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07DTM
|
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| Former ID |
DIB000157
|
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| Drug Name |
Cetraxal Otic
|
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| Synonyms |
Ciprofloxacin otic
|
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| Company |
Salvat Laboratories
|
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| Target and Pathway | |||||
| Target(s) | Topoisomerase IV subunit A | Target Info | Modulator | [530962], [538048], [544493] | |
| DNA gyraseA subunit | Target Info | Modulator | [530962], [538048], [544493] | ||
| References | |||||
| Ref 530962 | DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem Biol. 2010 May 28;17(5):421-33. | ||||
| Ref 538048 | DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. | ||||
| Ref 544493 | Selective Targeting of Topoisomerase IV and DNA Gyrase in Staphylococcus aureus: Different Patterns of Quinolone- Induced Inhibition of DNA Synthesis. Antimicrob Agents Chemother. 2000 August; 44(8):2160-2165. | ||||
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