TTD | Drug: D06XRS

Drug General Information
Drug ID	D06XRS
Former ID	DNC007756
Drug Name	N-(2-(4-chlorobenzyloxy)-5-bromobenzyl)ethanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528689]
Structure		Download 2D MOL 3D MOL
Formula	C16H17BrClNO
Canonical SMILES	CCNCC1=C(C=CC(=C1)Br)OCC2=CC=C(C=C2)Cl
InChI	1S/C16H17BrClNO/c1-2-19-10-13-9-14(17)5-8-16(13)20-11-12-3-6-15(18)7-4-12/h3-9,19H,2,10-11H2,1H3
InChIKey	ORVDFXFQIBURPI-UHFFFAOYSA-N
PubChem Compound ID	4716524
Target and Pathway
Target(s)	C-C chemokinereceptor type 5	Target Info	Inhibitor	[528689]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Endocytosis
	Toxoplasmosis
	Viral carcinogenesis
NetPath Pathway	TSLP Signaling Pathway
	TCR Signaling Pathway
	IL2 Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database	IL12-mediated signaling events
Reactome	Binding and entry of HIV virion
	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	TCR Signaling Pathway
	GPCRs, Class A Rhodopsin-like
	HIV Life Cycle
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 528689	Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. Epub 2007 Jan 25.CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives.
Ref 528689	Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. Epub 2007 Jan 25.CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives.

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Drug Information