Drug Information

Drug General Information
Drug ID
D06VYT
Former ID
DNC002699
Drug Name
O2-Sulfo-Glucuronic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
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2D MOL

3D MOL
Formula
C6H10O10S
Canonical SMILES
C1(C(C(OC(C1OS(=O)(=O)O)O)C(=O)O)O)O
InChI
1S/C6H10O10S/c7-1-2(8)4(16-17(12,13)14)6(11)15-3(1)5(9)10/h1-4,6-8,11H,(H,9,10)(H,12,13,14)/t1?,2-,3+,4+,6+/m0/s1
InChIKey
COJBCAMFZDFGFK-GLEQDHKKSA-N
PubChem Compound ID
11963648
PubChem Substance ID
820836, 7888326
Target and Pathway
Target(s) Hepatocyte growth factor Target Info Inhibitor [551393]
Heparin-binding growth factor1 Target Info Inhibitor [551393]
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
Malaria
Pathways in cancer
Proteoglycans in cancer
Renal cell carcinoma
Melanomahsa04010:MAPK signaling pathway
Hippo signaling pathway
Regulation of actin cytoskeleton
Melanoma
NetPath Pathway EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
TNFalpha Signaling Pathway
PANTHER Pathway Angiogenesis
FGF signaling pathway
Pathway Interaction Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Arf6 signaling events
Signaling events mediated by TCPTP
Direct p53 effectors
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Syndecan-1-mediated signaling events
Stabilization and expansion of the E-cadherin adherens junction
FGF signaling pathwayfgf_pathway:FGF signaling pathway
Reactome Platelet degranulation
Interleukin-7 signalingR-HSA-109704:PI3K Cascade
PIP3 activates AKT signaling
FGFR4 ligand binding and activation
FGFR3c ligand binding and activation
FGFR2c ligand binding and activation
FGFR2b ligand binding and activation
FGFR3 mutant receptor activation
Activated point mutants of FGFR2
Constitutive Signaling by Aberrant PI3K in Cancer
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade
Phospholipase C-mediated cascade
Phospholipase C-mediated cascade
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
FRS-mediated FGFR4 signaling
SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
Negative regulation of FGFR3 signaling
Negative regulation of FGFR4 signaling
RAF/MAP kinase cascade
WikiPathways Signaling of Hepatocyte Growth Factor Receptor
Focal Adhesion
NRF2 pathway
Nuclear Receptors Meta-Pathway
Extracellular vesicle-mediated signaling in recipient cells
Differentiation Pathway
Interleukin-7 signaling
Prostate CancerWP51:Regulation of Actin Cytoskeleton
Hair Follicle Development: Organogenesis (Part 2 of 3)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
PIP3 activates AKT signaling
Integrated Pancreatic Cancer Pathway
Signaling by FGFR
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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