Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06VVV
|
||||
| Former ID |
DNC010386
|
||||
| Drug Name |
NSC-348926
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H13NO6
|
||||
| Canonical SMILES |
C1=CC=C2C(=C1)C(=O)N(C2=O)C(CCCC(=O)O)C(=O)O
|
||||
| InChI |
1S/C14H13NO6/c16-11(17)7-3-6-10(14(20)21)15-12(18)8-4-1-2-5-9(8)13(15)19/h1-2,4-5,10H,3,6-7H2,(H,16,17)(H,20,21)
|
||||
| InChIKey |
WJNORNDVKYKEGX-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA (cytosine-5)-methyltransferase | Target Info | Inhibitor | [1] | |
| DNA (cytosine-5)-methyltransferase 3B | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Cysteine and methionine metabolism | ||||
| Metabolic pathways | |||||
| MicroRNAs in cancer | |||||
| Reactome | PRC2 methylates histones and DNA | ||||
| NoRC negatively regulates rRNA expression | |||||
| DNA methylation | |||||
| WikiPathways | Mesodermal Commitment Pathway | ||||
| Endoderm Differentiation | |||||
| Trans-sulfuration and one carbon metabolism | |||||
| One Carbon Metabolism | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2010 Jan 15;18(2):822-9. Epub 2009 Nov 27.Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.