TTD | Drug: D06RAM

Drug General Information
Drug ID	D06RAM
Former ID	DIB020384
Drug Name	MM 11253
Synonyms	MM-11253; MM11253
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540657]
Structure		Download 2D MOL
Formula	C28H30O2S2
InChI	InChI=1S/C28H30O2S2/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30)
InChIKey	DPVGXUNWCVEIGT-UHFFFAOYSA-N
PubChem Compound ID	10389639
PubChem Substance ID	15405236, 34109247, 74526726, 140288021, 163125606, 178100886, 204366766, 229468642, 241376650, 248879036, 249617992, 252109994, 252157558
Target and Pathway
Target(s)	Retinoic acid receptor gamma	Target Info	Antagonist	[525726]
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Vitamin A and Carotenoid Metabolism
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Mesodermal Commitment Pathway
	Endoderm Differentiation
	Nuclear Receptors
References
Ref 540657	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4062).
Ref 525726	Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids. Oncogene. 2000 Mar 9;19(11):1457-65.

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Drug Information