Drug Information
Drug General Information | |||||
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Drug ID |
D06PHE
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Former ID |
DIB019657
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Drug Name |
CPPG
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Synonyms |
cyclopropyl-4-phosphonophenylglycine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [538890] | ||
Structure |
Download2D MOL |
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Formula |
C11H14NO5P
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InChI |
InChI=1S/C11H14NO5P/c12-11(10(13)14,7-1-2-7)8-3-5-9(6-4-8)18(15,16)17/h3-7H,1-2,12H2,(H,13,14)(H2,15,16,17)
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InChIKey |
IGODGTDUQSMDQU-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Metabotropic glutamate receptor 4 | Target Info | Antagonist | [525456] | |
Metabotropic glutamate receptor 8 | Target Info | Antagonist | [525723] | ||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Metabotropic glutamate receptor group III pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
Metabotropic glutamate receptor group III pathway | |||||
References | |||||
Ref 525456 | Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor. J Biol Chem. 1999 Apr 9;274(15):10008-13. | ||||
Ref 525723 | Constraints on proper folding of the amino terminal domains of group III metabotropic glutamate receptors. Brain Res Mol Brain Res. 2000 Mar 10;76(1):180-90. |
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