Drug Information
Drug General Information | |||||
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Drug ID |
D06KHR
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Former ID |
DIB019709
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Drug Name |
decavanadate
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539586] | ||
Structure |
Download2D MOL |
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Formula |
O28V10-6
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InChI |
InChI=1S/28O.10V/q;;;;;;;;;;;;;;;;;;;;;;6*-1;;;;;;;;;;
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InChIKey |
OSBWBKHFRWKREF-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | P2X purinoceptor 7 | Target Info | Antagonist | [528045] | |
TRPM4 | Target Info | Activator | [527184] | ||
IP3R3 | Target Info | Antagonist | [543957] | ||
IP3R2 | Target Info | Antagonist | [543956] | ||
IP3R1 | Target Info | Antagonist | [543955] | ||
Reactome | The NLRP3 inflammasome | ||||
References | |||||
Ref 527184 | Decavanadate modulates gating of TRPM4 cation channels. J Physiol. 2004 Nov 1;560(Pt 3):753-65. Epub 2004 Aug 26. | ||||
Ref 528045 | Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors. Eur J Pharmacol. 2006 Mar 18;534(1-3):19-29. Epub 2006 Feb 17. | ||||
Ref 543955 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 743). | ||||
Ref 543956 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 744). | ||||
Ref 543957 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 745). |
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