Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06GJW
|
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| Former ID |
DNC001033
|
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| Drug Name |
Noradrenaline
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C8H11NO3
|
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| InChI |
InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2
|
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| InChIKey |
SFLSHLFXELFNJZ-UHFFFAOYSA-N
|
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| CAS Number |
CAS 51-41-2
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
146522, 219187, 3137157, 5633844, 8150886, 10318916, 10507475, 11534313, 15194998, 24439308, 47217070, 47365471, 49892615, 49892616, 51036043, 51075402, 57320616, 85209636, 85753313, 90341653, 103114946, 104296333, 104671918, 117616920, 118510068, 124749407, 125308191, 125351846, 125543283, 125617113, 126608921, 126632801, 126678538, 129228531, 134973927, 134975595, 135651526, 137001235, 140204844, 143512633, 162250799, 162871635, 164788400, 166426611, 176223939, 179116819, 198992584, 215780277, 223435936, 226395016
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| ChEBI ID |
ChEBI:18357
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| SuperDrug ATC ID |
C01CA03
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| SuperDrug CAS ID |
cas=000051412
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| Target and Pathway | |||||
| Target(s) | Beta-1 adrenergic receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| cGMP-PKG signaling pathway | |||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Endocytosis | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Gap junction | |||||
| Salivary secretion | |||||
| Dilated cardiomyopathy | |||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Beta1 adrenergic receptor signaling pathway | |||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | Adrenoceptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| Calcium Regulation in the Cardiac Cell | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Endothelin Pathways | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 484). | ||||
| REF 2 | Classification of the beta-adrenoceptor subtype in the rat portal vein: effect of altered thyroid hormone levels. Eur J Pharmacol. 1992 Mar 3;212(2-3):201-7. | ||||
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