Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D06FDR
|
||||
Former ID |
DAP000702
|
||||
Drug Name |
Didanosine
|
||||
Synonyms |
DDI; DIDEOXYINOSINE; DdIno; Didanosina; Didanosinum; Videx; Hypoxanthine ddN; Videx EC; BMY 40900; BMY-40900; DRG-0016; DdI + d4T combination; Didanosina [INN-Spanish]; Didanosinum [INN-Latin]; Dideoxyinosine (DDI); Intron A & Videx; KS-1049; LOA & ddI; Videx (TN); Videx EC (TN); Videx(TM); DDI and rIFN.alpha.2; DS-4152 & ddI; DdI & GM-CSF; DdI & IFN-alpha; DdI & sCD4(rsCD4); PC-SOD+ddI; Didanosine (JAN/USAN/INN); Videx EC(TM)(slow-release capsules); Didanosine and Interferon-.alpha.-2; Listera ovata agglutinin & 2',3'-Dideoxyinosine; Sulfated polysaccharide-peptidoglycan DS-4152 & 2',3'-Dideoxyinosine; Inosine, 2',3'-dideoxy-& Recombinant Interferon-.alpha.-2; 2',3'-Dideoxyinosine; 2',3'-Dideoxyinosine & Granulocyte-macrophage colony-stimulating factor; 2',3'-Dideoxyinosine & Interferon-alpha; 2',3'-Dideoxyinosine & sCD4(soluble recombinant protein); 2',3'-Dideoxyinosine (AIDS Initiative); 2',3'-Dideoxyinosine (ddI); 2',3'-dideoxyinosine, DDI, NSC 612049, Didanosine; 2'3'-DIDEOXYINOSINE; 2,3-dideoxyinosine; 3'-Azido-3'-deoxythymidine + 2',3'-Dideoxyinosine; 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one; 9-(2,3-Dideoxy-beta-D-ribofuranosyl)-6-oxopurine; 9-(2,3-Dideoxy-beta-D-ribofuranosyl)hypoxanthine; 9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE; 9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one; 9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; DDI
|
||||
Drug Type |
Small molecular drug
|
||||
Therapeutic Class |
Anti-HIV Agents
|
||||
Company |
Bristol-Myers Squibb
|
||||
Structure |
Download2D MOL |
||||
Formula |
C10H12N4O3
|
||||
InChI |
InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1
|
||||
InChIKey |
BXZVVICBKDXVGW-NKWVEPMBSA-N
|
||||
CAS Number |
CAS 69655-05-6
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
9168, 595889, 596438, 596681, 597344, 601538, 602978, 622273, 833736, 7847362, 7885163, 7979070, 7979071, 12014245, 14847321, 15121787, 15121788, 15196316, 17389541, 22431600, 25819905, 26719672, 26754510, 26757698, 29215491, 34715128, 46386730, 46506255, 46508438, 48415887, 48422196, 48422428, 48423223, 48424479, 49681777, 49718183, 56463354, 57313303, 58717761, 77794640, 81093234, 87351572, 87559876, 90451743, 91612512, 92308421, 92308956, 92711314, 92729668, 103529091
|
||||
SuperDrug ATC ID |
J05AF02
|
||||
SuperDrug CAS ID |
cas=069655056
|
||||
Drug Resistance Mutation (DRM) | |||||
DRM | DRM Info | ||||
Target and Pathway | |||||
Target(s) | HIV reverse transcriptase | Target Info | Inhibitor | [537278] | |
References | |||||
Ref 468066 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4833). | ||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.