Drug Information
Drug General Information | |||||
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Drug ID |
D06EZQ
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Former ID |
DNC007575
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Drug Name |
GRANULATIMIDE
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [528838] | ||
Structure |
Download2D MOL |
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Formula |
C15H8N4O2
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Canonical SMILES |
C1=CC=C2C(=C1)C3=C4C(=C5C(=C3N2)NC=N5)C(=O)NC4=O
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InChI |
1S/C15H8N4O2/c20-14-9-8-6-3-1-2-4-7(6)18-12(8)13-11(16-5-17-13)10(9)15(21)19-14/h1-5,18H,(H,16,17)(H,19,20,21)
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InChIKey |
LBTREMHIJGMYQN-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Serine/threonine-protein kinase Chk1 | Target Info | Inhibitor | [528838] | |
Pathway Interaction Database | Fanconi anemia pathway | ||||
p73 transcription factor network | |||||
ATR signaling pathway | |||||
Circadian rhythm pathway | |||||
p53 pathway | |||||
Reactome | Activation of ATR in response to replication stress | ||||
Processing of DNA double-strand break ends | |||||
Presynaptic phase of homologous DNA pairing and strand exchange | |||||
G2/M DNA damage checkpoint | |||||
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |||||
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |||||
References |
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