Drug Information

Drug General Information
Drug ID
D06BCB
Former ID
DAP001437
Drug Name
Vinpocetine
Synonyms
Bravinton; Cavinton; Ceractin; Vinpocetinum; Apovincaminic acid ethyl ester; AY 27255; RGH 4405; TCV 3B; V 6383; V6383_SIGMA; AY 27,255; Apovincaminate d'ethyle; Apovincaminate d'ethyle [French]; Cavinton (TN); Cis-Apovincaminic acid ethyl ester; Intelectol (TN); RGH-4405; TCV-3B; Ultra-Vinca; Vinpocetine-ethyl apovincaminate; Vinpocetinum [INN-Latin]; Eburnamenine-14-carboxylic acid ethyl ester; Ethyl apovincamin-22-oate; Vinpocetine [USAN:INN:JAN]; Ethyl (+)-apovincaminate; Vinpocetine (JAN/USAN/INN); Ethyl(+)-cis-apovincaminate; Ethyl apovincaminate, (3alpha,16alpha)-isomer; Ethyl (3alpha,16alpha)-eburnamenine-14-carboxylate; (+)-Apovincaminic acid ethyl ester; (+)-cis-Apovincaminic acid ethyl ester; (3alpha, 16alpha)-Eburnamenine-14-carboxylic acid ethyl ester; 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic acid deriv.; 3-alpha,16-alpha-Apovincaminic acid ethyl ester
Drug Type
Small molecular drug
Indication Acute ischemic stroke [ICD9: 434.91; ICD10:I61-I63] Approved [537150], [540748]
Therapeutic Class
Vasodilator Agents
Structure
Download
2D MOL

3D MOL
Formula
C22H26N2O2
InChI
InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1
InChIKey
DDNCQMVWWZOMLN-IRLDBZIGSA-N
CAS Number
CAS 42971-09-5
PubChem Compound ID
443955
PubChem Substance ID
855619, 3727081, 7848434, 7980299, 10299443, 10321872, 11341598, 11361781, 11364294, 11366856, 11369418, 11371881, 11374568, 11377580, 11466296, 11467416, 11485054, 11486071, 11487183, 11489345, 11490776, 11492889, 11495214, 14802886, 14925387, 17405811, 24278182, 26612408, 26680355, 26759739, 36887098, 47216903, 47365339, 47440398, 47810892, 47959906, 48334637, 48334638, 48416699, 48483328, 49698412, 49964760, 50103960, 50103961, 50103962, 50103963, 50113284, 53778363, 53790458, 56424092
SuperDrug ATC ID
N06BX18
SuperDrug CAS ID
cas=042971095
Target and Pathway
Target(s) Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 Target Info Inhibitor [537150]
References
Ref 537150Effects of phosphodiesterase inhibitors on contraction induced by endothelin-1 of isolated human prostatic tissue. Urology. 2009 Jun;73(6):1397-401. Epub 2009 Mar 13.
Ref 540748(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5285).
Ref 537150Effects of phosphodiesterase inhibitors on contraction induced by endothelin-1 of isolated human prostatic tissue. Urology. 2009 Jun;73(6):1397-401. Epub 2009 Mar 13.

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