Drug Information

Drug General Information
Drug ID
D06BBF
Former ID
DIB004752
Drug Name
BLV-0801
Synonyms
SBLK-200801; IDO inhibitor (CNS disorders), Bioalvo; Indoleamine dioxygenase inhibitor (CNS disorders), Bioalvo
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543722]
Company
Bioalvo SA
Target and Pathway
Target(s) Indoleamine 2,3-dioxygenase Target Info Inhibitor [543722]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation
L-kynurenine degradation
Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
NAD de novo biosynthesis
KEGG Pathway Tryptophan metabolism
Metabolic pathways
African trypanosomiasis
NetPath Pathway TSLP Signaling Pathway
IL5 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Tryptophan Metabolism
Reactome Tryptophan catabolism
WikiPathways Tryptophan metabolism
Metabolism of amino acids and derivatives
References
Ref 543722(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2829).
Ref 543722(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2829).

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