Drug Information
Drug General Information | |||||
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Drug ID |
D05UQD
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Former ID |
DCL000188
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Drug Name |
Omapatrilat
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Synonyms |
BMS-186716; Omapatrilat (JAN/USAN/INN); (4S,7S,10aS)-5-oxo-4-[[(2S)-3-phenyl-2-sulfanylpropanoyl]amino]-2,3,4,7,8,9,10,10a-octahydropyrido[2,1-b][1,3]thiazepine-7-carboxylic acid
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Terminated | [526007] | ||
Company |
Bristol-Myers Squibb
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Structure |
Download2D MOL |
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Formula |
C19H24N2O4S2
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Canonical SMILES |
C1CC(N2C(C1)SCCC(C2=O)NC(=O)C(CC3=CC=CC=C3)S)C(=O)O
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InChI |
1S/C19H24N2O4S2/c22-17(15(26)11-12-5-2-1-3-6-12)20-13-9-10-27-16-8-4-7-14(19(24)25)21(16)18(13)23/h1-3,5-6,13-16,26H,4,7-11H2,(H,20,22)(H,24,25)/t13-,14-,15-,16-/m0/s1
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InChIKey |
LVRLSYPNFFBYCZ-VGWMRTNUSA-N
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CAS Number |
CAS 167305-00-2
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Neutral endopeptidase | Target Info | Modulator | [526007] | |
Angiotensin-converting enzyme | Target Info | Modulator | [526007] | ||
NetPath Pathway | EGFR1 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
References |
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