Drug Information
Drug General Information | |||||
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Drug ID |
D05UMD
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Former ID |
DIB014591
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Drug Name |
R-87366
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Synonyms |
Quinoxalin-2-ylcarbonyl-L-asparaginyl-[3(S)-amino-2(S)-hydroxy-4-phenylbutyryl]-L-proline tert-butylamide
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Drug Type |
Small molecular drug
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Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Discontinued in Phase 2 | [546555] | ||
Structure |
Download2D MOL |
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Formula |
C32H39N7O6
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Canonical SMILES |
CC(C)(C)NC(=O)C1CCCN1C(=O)C(C(CC2=CC=CC=C2)NC(=O)C(CC(=<br />O)N)NC(=O)C3=NC4=CC=CC=C4N=C3)O
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InChI |
1S/C32H39N7O6/c1-32(2,3)38-30(44)25-14-9-15-39(25)31(45)27(41)22(16-19-10-5-4-6-11-19)36-28(42)23(17-26(33)40)37-29(43)24-18-34-20-12-7-8-13-21(20)35-24/h4-8,10-13,18,22-23,25,27,41H,9,14-17H2,1-3H3,(H2,33,40)(H,36,42)(H,37,43)(H,38,44)/t22-,23-,25-,27-/m0/s1
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InChIKey |
UYZMZENNYRSFDS-QNWDWTFCSA-N
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CAS Number |
CAS 144779-91-9
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | HIV protease | Target Info | Inhibitor | [534336], [551871] | |
References | |||||
Ref 534336 | In vitro and ex vivo anti-human immunodeficiency virus (HIV) activities of a new water-soluble HIV protease inhibitor, R-87366, containing (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid. Biol Pharm Bull. 1997 Feb;20(2):175-80. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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