Drug Information

Drug General Information
Drug ID
D05UBX
Former ID
DAP001179
Drug Name
Cefmetazole
Synonyms
CMZ; Cefmetazolo; Cefmetazolum; Cefmetazole Monosodium Salt; CS 1170; SKF 83088; U 72791; CS-1170; Cefmetazole [USAN:INN]; Cefmetazolo [INN-Spanish]; Cefmetazolum [INN-Latin]; U-72791A; Cefmetazole (USP/INN); (6R,7S)-7-(2-((Cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid; (6R,7S)-7-(2-((Cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, sodium salt; (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7S)-7-({[(cyanomethyl)thio]acetyl}amino)-7-(methyloxy)-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 6beta-{[(cyanomethyl)sulfanyl]acetamido}-6alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}ceph-3-em-4-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [538602]
Therapeutic Class
Antibiotics
Company
Pharmacia And Upjohn Co
Structure
Download
2D MOL

3D MOL
Formula
C15H17N7O5S3
Canonical SMILES
CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O<br />)O
InChI
1S/C15H17N7O5S3/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25)/t13-,15+/m1/s1
InChIKey
SNBUBQHDYVFSQF-HIFRSBDPSA-N
CAS Number
CAS 56796-20-4
PubChem Compound ID
42008
PubChem Substance ID
10303, 632166, 7847973, 7978876, 8177398, 11466728, 11467848, 11486516, 15479323, 34707577, 46504461, 47217057, 47217058, 47440545, 47440546, 48259496, 48415716, 50050974, 50294685, 57312636, 58106756, 92251462, 92712300, 104338473, 123087792, 124766309, 126625684, 126686221, 131319170, 134224281, 134338424, 135002546, 135882605, 136357157, 137006381, 140396436, 152035638, 160963622, 162173144, 164788224, 175442148, 179150673, 184544918, 198970111, 223674319, 226513671, 251916490, 251917837, 252347145, 252449370
ChEBI ID
ChEBI:3489
SuperDrug ATC ID
J01DC09
SuperDrug CAS ID
cas=056796204
Target and Pathway
Target(s) Penicillin binding protein 3 Target Info Binder [538144]
References
Ref 538602FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 050637.
Ref 538144Clinical relevance of antibiotic-induced endotoxin release in patients undergoing hepatic resection. World J Surg. 1999 Jan;23(1):75-9.

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