Drug Information

Drug General Information
Drug ID
D05TXS
Former ID
DIB012458
Drug Name
BMN-168
Synonyms
Sapropterin prodrug, BioMarin; 6R-BH4 prodrug, BioMarin
Indication Phenylketonuria [ICD10:E70.0] Investigative [543386]
Company
BioMarin Pharmaceutical Inc
Target and Pathway
Target(s) Phenylalanine hydroxylase Target Info Modulator [543386]
BioCyc Pathway Phenylalanine degradation/tyrosine biosynthesis
KEGG Pathway Phenylalanine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of amino acids
PathWhiz Pathway Phenylalanine and Tyrosine Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Metabolism of amino acids and derivatives
Abnormal metabolism in phenylketonuria
References
Ref 543386(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1240).
Ref 543386(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1240).

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