Drug Information

Drug General Information
Drug ID
D04UKJ
Former ID
DIB009025
Drug Name
NP-61
Synonyms
Dual binding site acetylcholinesterase inhibitor, Neuropharma; NP-00361; NP-0361; AChE inhibitor (Alzheimer's) Neuropharma (Zeltia); AChE inhibitor/beta amyloid secretion inhibitor (oral formulation, Alzheimer's disease), Noscira
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Discontinued in Phase 1 [548783]
Company
Noscira SA
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [525350]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 548783Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028783)
Ref 525350Potent beta-amyloid modulators. Neurodegener Dis. 2008;5(3-4):153-6.

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