Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04TSO
|
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| Former ID |
DIB002751
|
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| Drug Name |
UNBS-1450
|
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| Synonyms |
UNBS-1244; Na+ K+ ATPase inhibitor, (intravenous, cancer), Unibioscreen; 2''-oxovoruscharin
|
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| Drug Type |
Small molecular drug
|
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| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Phase 1 | [548863] | ||
| Company |
Unibioscreen SA
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C31H43NO9S
|
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| Canonical SMILES |
[C@@]12(SCC(=O)N1)[C@@]1(O[C@@H]3C[C@]4([C@H](C[C@H]3O[<br />C@@H]1O[C@@H](C2)C)CC[C@@H]1[C@@H]4CC[C@]2([C@@]1(CC[C@<br />@H]2C1=CC(=O)OC1)O)C)CO)O
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium/potassium-transporting ATPase alpha-1 chain | Target Info | Inhibitor | [533266] | |
| KEGG Pathway | cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | |||||
| Cardiac muscle contraction | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Insulin secretion | |||||
| Thyroid hormone synthesis | |||||
| Thyroid hormone signaling pathway | |||||
| Aldosterone-regulated sodium reabsorption | |||||
| Endocrine and other factor-regulated calcium reabsorption | |||||
| Proximal tubule bicarbonate reclamation | |||||
| Salivary secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Carbohydrate digestion and absorption | |||||
| Protein digestion and absorption | |||||
| Bile secretion | |||||
| Mineral absorption | |||||
| Reactome | Ion transport by P-type ATPases | ||||
| WikiPathways | Iron uptake and transport | ||||
| References | |||||
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