Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04RNU
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| Former ID |
DNC004354
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| Drug Name |
6-Benzyloxy-5-nitroso-pyrimidine-2,4-diamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C11H11N5O2
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| Canonical SMILES |
C1=CC=C(C=C1)COC2=NC(=NC(=C2N=O)N)N
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| InChI |
1S/C11H11N5O2/c12-9-8(16-17)10(15-11(13)14-9)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,12,13,14,15)
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| InChIKey |
MBQPVHNJEDDVCF-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Methylated-DNA--protein-cysteine methyltransferase | Target Info | Inhibitor | [1] | |
| WikiPathways | DNA Damage Reversal | ||||
| References | |||||
| REF 1 | J Med Chem. 1998 Feb 12;41(4):503-8.Inhibition of human O6-alkylguanine-DNA alkyltransferase and potentiation of the cytotoxicity of chloroethylnitrosourea by 4(6)-(benzyloxy)-2,6(4)-diamino-5-(nitroor nitroso)pyrimidine derivatives and analogues. | ||||
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