Drug Information
Drug General Information | |||||
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Drug ID |
D04MPB
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Former ID |
DIB009821
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Drug Name |
Bevirimat
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Synonyms |
DSB; Bevirimat dimeglumine; DSB 2NMG; MPC-4326; PA-457; PA-103001-01; PA-103001-04; PA-457 di-NMG; Viral maturation inhibitor (HIV), Myrexis; Viral maturation inhibitor (HIV), Myriad; Viral maturation inhibitor (HIV), Panacos; YK-FH-312; 3-O-(3' 3'-dimethylsuccinyl)-betulinic acid
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Drug Type |
Small molecular drug
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Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 2 | [522771] | ||
Company |
Panacos
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Structure |
Download2D MOL |
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Formula |
C36H56O6
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Canonical SMILES |
[C@@]12([C@]3([C@@H]([C@@]4([C@H](C([C@@H](OC(=O)CC(C(=<br />O)O)(C)C)CC4)(C)C)CC3)C)CC[C@@H]1[C@@H]1[C@@](C(=O)O)(C<br />C2)CC[C@H]1C(=C)C)C)C
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | HIV GAG protein | Target Info | Inhibitor | [532230] | |
Reactome | Uncoating of the HIV Virion | ||||
Budding and maturation of HIV virion | |||||
Integration of provirus | |||||
Early Phase of HIV Life Cycle | |||||
Minus-strand DNA synthesis | |||||
Plus-strand DNA synthesis | |||||
2-LTR circle formation | |||||
Binding and entry of HIV virion | |||||
Membrane binding and targetting of GAG proteins | |||||
Assembly Of The HIV Virion | |||||
Integration of viral DNA into host genomic DNA | |||||
Autointegration results in viral DNA circles | |||||
APOBEC3G mediated resistance to HIV-1 infection | |||||
Vpr-mediated nuclear import of PICs | |||||
WikiPathways | Host Interactions of HIV factors | ||||
HIV Life Cycle | |||||
References |
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