Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04LBV
|
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| Former ID |
DIB018927
|
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| Drug Name |
AZ4800
|
||||
| Synonyms |
AZ 4800; AZ-4800
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [531800] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C24H29N5O3
|
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| InChI |
InChI=1S/C24H29N5O3/c1-16-12-29(15-25-16)22-8-7-17(11-23(22)30-2)26-24-27-20-9-10-31-13-19(20)21(28-24)14-32-18-5-3-4-6-18/h7-8,11-12,15,18H,3-6,9-10,13-14H2,1-2H3,(H,26,27,28)
|
||||
| InChIKey |
RMRFSIAFQBYBSN-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [531800] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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