Drug Information

Drug General Information
Drug ID
D04FXS
Former ID
DNC000557
Drug Name
Didox
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Discontinued in Phase 2 [545210]
Structure
Download
2D MOL

3D MOL
Formula
C7H7NO4
Canonical SMILES
C1=CC(=C(C=C1C(=O)NO)O)O
InChI
1S/C7H7NO4/c9-5-2-1-4(3-6(5)10)7(11)8-12/h1-3,9-10,12H,(H,8,11)
InChIKey
QJMCKEPOKRERLN-UHFFFAOYSA-N
CAS Number
CAS 69839-83-4
PubChem Compound ID
3045
PubChem Substance ID
457824, 634609, 5632198, 8151938, 11407208, 12013951, 15066661, 15171157, 29222191, 49877397, 50731210, 57321575, 71822596, 103433469, 103834548, 104302366, 117562122, 125335454, 127274074, 127274075, 127274076, 127274077, 127274078, 127274079, 127274080, 127274081, 127274082, 127274083, 127274084, 127274085, 127274086, 127274087, 127274088, 127274089, 127274090, 127274091, 127274092, 127274093, 127274094, 127274095, 127274096, 127274097, 127274098, 127274099, 127274100, 127274101, 127274102, 127274103, 127274104, 127274105
Target and Pathway
Target(s) Ribonucleoside-diphosphate reductase Target Info Inhibitor [535646]
References
Ref 545210Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002464)
Ref 535646Didox (a novel ribonucleotide reductase inhibitor) overcomes Bcl-2 mediated radiation resistance in prostate cancer cell line PC-3. Cancer Biol Ther. 2002 Sep-Oct;1(5):539-45.

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