Drug Information
Drug General Information | |||||
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Drug ID |
D04FTL
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Former ID |
DNC003253
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Drug Name |
3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [551374] | ||
Structure |
Download2D MOL |
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Formula |
C14H10N4
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Canonical SMILES |
C1=CC=C2C(=C1)C(=C3N=C4C=CC=CC4=N3)NN2
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InChI |
1S/C14H10N4/c1-2-6-10-9(5-1)13(18-17-10)14-15-11-7-3-4-8-12(11)16-14/h1-8,17-18H
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InChIKey |
ULAJWYXWWHKJNG-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Serine/threonine-protein kinase Chk1 | Target Info | Inhibitor | [551374] | |
Pathway Interaction Database | Fanconi anemia pathway | ||||
p73 transcription factor network | |||||
ATR signaling pathway | |||||
Circadian rhythm pathway | |||||
p53 pathway | |||||
Reactome | Activation of ATR in response to replication stress | ||||
Processing of DNA double-strand break ends | |||||
Presynaptic phase of homologous DNA pairing and strand exchange | |||||
G2/M DNA damage checkpoint | |||||
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |||||
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |||||
References |
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