Drug Information

Drug General Information
Drug ID
D03ZBN
Former ID
DNC001058
Drug Name
Olprinone
Drug Type
Small molecular drug
Indication Heart failure [ICD9: 428; ICD10:I50] Approved [544653], [551871]
Structure
Download
2D MOL

3D MOL
Formula
C14H10N4O
Canonical SMILES
CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2
InChI
1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)
InChIKey
JPAWFIIYTJQOKW-UHFFFAOYSA-N
CAS Number
CAS 119615-63-3
PubChem Compound ID
4593
PubChem Substance ID
4696241, 8152818, 15221182, 26755731, 29216409, 29223682, 50031333, 50783351, 57322339, 90340623, 96024981, 103816637, 104306853, 117512868, 126682944, 128306867, 134340309, 135132659, 137263841, 163620782, 163686107, 164228291, 164814836, 172658312, 174007056, 179149678, 184546129, 184828787, 198984786, 215779060, 223653998, 224893184, 226415186, 242277329, 252480352
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase Target Info Inhibitor [535590]
References
Ref 544653Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000438)
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535590Olprinone: a phosphodiesterase III inhibitor with positive inotropic and vasodilator effects. Cardiovasc Drug Rev. 2002 Fall;20(3):163-74.

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