Drug General Information
Drug ID	D03WPI
Former ID	DIB001826
Drug Name	NC-190
Synonyms	NCU-190Na
Drug Type	Small molecular drug
Indication	Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48]		Discontinued in Phase 2	[544763]
Company	Taisho Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Formula	C23H21N4NaO5
Canonical SMILES	c12c(c(c(c3c1cccc3)O)C(=O)NCCN(C)C)nc1c(n2)cc(c(c1)C(=O<br />)[O-])OC.[Na+]
PubChem Compound ID	23663980
Target and Pathway
Target(s)	DNA topoisomerase II	Target Info	Modulator	[526888]
References
Ref 544763	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000904)
Ref 526888	The topoisomerase II-inhibitor NC-190 reduces the level of thymidine kinase mRNA in murine tumor cells. Res Commun Mol Pathol Pharmacol. 2002;111(1-4):77-87.

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