Drug General Information
Drug ID
D03VPC
Former ID
DAP000191
Drug Name
Cilostazol
Synonyms
Cilostazole; Cilostazolum; Pletaal; Pletal; Otsuka brand of cilostazol; C 0737; CL23867; OPC 13013; OPC 21; Cilostazol [INN:JAN]; Cilostazolum [INN-Latin]; OPC-13013; OPC-21; Pleta (TN); Pletal (TN); Pletal, Cilostazol; Cilostazol (JP15/USAN/INN); 3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril; 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone; 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one; 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
Drug Type
Small molecular drug
Indication Intermittent claudication [ICD9: 440.21; ICD10:I73.9] Approved [536186], [542155]
Therapeutic Class
Vasodilator Agents
Company
Otsuka Pharmaceutical Co
Structure
Download
2D MOL

3D MOL

Formula
C20H27N5O2
InChI
InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26)
InChIKey
RRGUKTPIGVIEKM-UHFFFAOYSA-N
CAS Number
CAS 73963-72-1
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
B01AC23
Target and Pathway
Target(s) Phosphodiesterase (PDE) 3 Target Info Modulator [556264]
References
Ref 536186Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
Ref 542155(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7148).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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