Drug General Information
Drug ID	D03UID
Former ID	DNC001218
Drug Name	RJR-2403
Drug Type	Small molecular drug
Indication	Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3]		Discontinued in Phase 2	[540610], [546260]
Structure		Download 2D MOL 3D MOL
Formula	C10H14N2
InChI	InChI=1S/C10H14N2/c1-11-7-3-2-5-10-6-4-8-12-9-10/h2,4-6,8-9,11H,3,7H2,1H3/b5-2+
InChIKey	JUOSGGQXEBBCJB-GORDUTHDSA-N
CAS Number	CAS 55088-60-3
PubChem Compound ID	5310967
PubChem Substance ID	111416, 609860, 7978539, 11056174, 15171050, 26752048, 39340703, 50032750, 50064512, 53091354, 57359305, 103129209, 103369533, 103957123, 114154935, 117521745, 132556611, 134224167, 135029806, 135253531, 136352882, 137001273, 137010080, 143156490, 152258469, 152344535, 160647304, 164229888, 164762647, 164780426, 175427044, 178100820, 198984640, 198992135, 223807308, 226492038, 226492039, 252479545
Target and Pathway
Target(s)	Nicotinic acetylcholine receptor	Target Info	Agonist	[535334]
References
Ref 540610	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3994).
Ref 546260	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007149)
Ref 535334	The therapeutic potential of nicotinic acetylcholine receptor agonists for pain control. Expert Opin Investig Drugs. 2001 Oct;10(10):1819-30.

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