Drug Information
Drug General Information | |||||
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Drug ID |
D03RNX
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Former ID |
DIB001692
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Drug Name |
EPC-K1
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Synonyms |
CHX-3107; Phosphoric acid 2-L-ascorbyl D,L-alpha-tocopheryl diester potassium salt; 2-O-[Hydroxy[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yloxy]phosphoryl]-L-ascorbic acid potassium salt
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Drug Type |
Small molecular drug
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Indication | Nerve injury [ICD10:T14.4] | Discontinued in Phase 2 | [546374] | ||
Structure |
Download2D MOL |
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Formula |
C35H57KO10P+
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Canonical SMILES |
CC1=C2C(=C(C(=C1C)OP(=O)(O)OC3=C(C(OC3=O)C(CO)O)O)C)CCC<br />(O2)(C)CCCC(C)CCCC(C)CCCC(C)C.[K+]
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InChI |
1S/C35H57O10P.K/c1-21(2)12-9-13-22(3)14-10-15-23(4)16-11-18-35(8)19-17-27-26(7)30(24(5)25(6)31(27)43-35)44-46(40,41)45-33-29(38)32(28(37)20-36)42-34(33)39;/h21-23,28,32,36-38H,9-20H2,1-8H3,(H,40,41);/q;+1/t22-,23-,28+,32-,35-;/m1./s1
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InChIKey |
VIHIKSJKXIMMLV-FZTHFCCHSA-N
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CAS Number |
CAS 127061-56-7
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Phospholipase A2 | Target Info | Inhibitor | [533699], [551871] | |
BioCyc Pathway | Phospholipases | ||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
WikiPathways | Glycerophospholipid biosynthesis | ||||
References | |||||
Ref 533699 | Posttreatment with EPC-K1, an inhibitor of lipid peroxidation and of phospholipase A2 activity, reduces functional deficits after global ischemia in rats. Brain Res Bull. 1995;36(3):257-60. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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