Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03HDP
|
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| Former ID |
DIB001065
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| Drug Name |
ACEA-1416
|
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| Synonyms |
Glystatin series member (1416), CoCensys
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| Indication | Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] | Terminated | [1] | ||
| Company |
Purdue Neuroscience Corp
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c12c([N+](=O)[O-])c(c(cc2[nH]c(=O)c(=O)[nH]1)Cl)C
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| CAS Number |
CAS 167415-33-0
|
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| Target and Pathway | |||||
| Target(s) | NMDA receptor | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007961) | ||||
| REF 2 | Tolerance develops to the antinociceptive and motor impairing effects of ACEA-1416, a NMDA receptor antagonist, in the formalin and rotarod test in mice. Pharmacol Res. 1998 Apr;37(4):295-302. | ||||
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