Drug Information
Drug General Information | |||||
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Drug ID |
D03GFW
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Former ID |
DNC001175
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Drug Name |
Pyrilamine Maleate
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C21H27N3O5
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Canonical SMILES |
CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O
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InChI |
1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
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InChIKey |
JXYWFNAQESKDNC-BTJKTKAUSA-N
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CAS Number |
CAS 59-33-6
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PubChem Compound ID | |||||
PubChem Substance ID |
70057, 855902, 8149511, 10321599, 11039284, 17405449, 24277797, 26611903, 26680596, 26747601, 26747602, 39317787, 47207321, 48414401, 48424022, 49854469, 50106737, 50106738, 50106739, 53777996, 56422415, 74505398, 87220220, 91011388, 92124194, 92125164, 92304336, 92307601, 99301263, 103770989, 103914089, 113862915, 121264371, 121361486, 121362835, 124637085, 124800889, 124800890, 134338608, 134340402, 134972293, 135697893, 144075206, 144207712, 144233404, 152090224, 162227138, 163564844, 172829020, 175266358
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SuperDrug ATC ID |
D04AA02; R06AC01
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SuperDrug CAS ID |
cas=000091849
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Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Antagonist | [536700], [537884] | |
PANTHER Pathway | Histamine H1 receptor mediated signaling pathway | ||||
References | |||||
Ref 536700 | Intact cell binding for in vitro prediction of sedative and non-sedative histamine H1-receptor antagonists based on receptor internalization. J Pharmacol Sci. 2008 May;107(1):66-79. Epub 2008 Apr 29. | ||||
Ref 537884 | Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. | ||||
Ref 536700 | Intact cell binding for in vitro prediction of sedative and non-sedative histamine H1-receptor antagonists based on receptor internalization. J Pharmacol Sci. 2008 May;107(1):66-79. Epub 2008 Apr 29. | ||||
Ref 537884 | Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. |
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