Drug Information

Drug General Information
Drug ID
D03DNV
Former ID
DIB018878
Drug Name
ARI-3099
Synonyms
compound 6 [PMID: 23594271]; compound 226 [PMID: 24997602]; Py(D)AlaboroPro
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532870]
Structure
Download
2D MOL
Formula
C13H18BN3O4
InChI
InChI=1S/C13H18BN3O4/c1-9(16-12(18)10-4-6-15-7-5-10)13(19)17-8-2-3-11(17)14(20)21/h4-7,9,11,20-21H,2-3,8H2,1H3,(H,16,18)/t9-,11+/m1/s1
InChIKey
DRBWRJPFNOBNIO-KOLCDFICSA-N
PubChem Compound ID
71655266
PubChem Substance ID
163818086, 164137747, 164160117, 184611046, 252166764
Target and Pathway
Target(s) Acylamino-acid-releasing enzyme Target Info Inhibitor [532870]
Seprase Target Info Inhibitor [532317]
References
Ref 532870A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat Chem Biol. 2014 Aug;10(8):656-63.
Ref 532317Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem. 2013 May 9;56(9):3467-77.
Ref 532870A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat Chem Biol. 2014 Aug;10(8):656-63.

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