Drug Information
Drug General Information | |||||
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Drug ID |
D03DDR
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Former ID |
DAP000491
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Drug Name |
Quinine
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Synonyms |
Aflukin; Chinin; Chinine; Chininum; Conchinin; Conquinine; Quindan; Quinidex; Quinidine; Quinimax; Quinina; Quinineanhydrous; Quinora; Quniacridine; Chinin [German]; Kinder Quinina; QUININE MONO HCL; Quinine Dab; Quinine [BAN]; Quinine anhydrous; Quinine bisulfate; Quinine sulfate; Quinine sulphate; Quinoline alkaloid; LT00645788;Q0028; SB01652; Beta-Quinine; Cin-Quin; Coco-Quinine; IBS-L0034250; Kinder Quinina (TN); Legatrin (TN); Quinine (BAN); Quinine, Anhydrous; Quinine, polymers; Quinine, tannate; Biquinate (*Bisulfate heptathydrate*); Dentojel (*Bisulfate heptathydrate*); Quinamm (*2:1 Sulfate salt*), dihydrate; Quine (*2:1 Sulfate salt*, dihydrate); Quinsan (*2:1 Sulfate salt*), dihydrate; Alpha-(6-Methoxy-4-quinoyl)-5-vinyl-2-quinclidinemethanol; Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)-, sulfate; (+)-Quinidine; (-)-Quinine; (1R)-(6-Methoxyquinolin-4-yl)((1S,4S,5R)-5-vinylquinuclidin-2-yl)methanol; (3A,8A,9r)-6'-methoxycinchonan-9-ol; (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol; (8-alpha,9R)-6'-Methoxycinchonan-9-ol; (8.alpha.,9R)-6'-Methoxycinchonan-9-ol; (8S,9R)-6'-Methoxycinchonan-9-ol; (8S,9R)-Quinine; (9R)-6'-methoxy-8alpha-cinchonan-9-ol; (R)-(-)-Quinine, 6-methoxycinchonidine; (R)-(-)-quinine; (R)-(6-Methoxy-quinolin-4-yl)-((2S,5S)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol; (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol; (R)-[(2S,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (R)-[(2S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (S)-(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol; (S)-[(2R,4R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; 6'-Methoxycinchonan-9-ol; 6'-Methoxycinchonidine; 6'-Methoxycinchonine; 6-Methoxycinchonine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antimalarials
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Company |
Pfizer Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C20H24N2O2
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InChI |
InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
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InChIKey |
LOUPRKONTZGTKE-WZBLMQSHSA-N
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CAS Number |
CAS 130-95-0
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PubChem Compound ID | |||||
PubChem Substance ID |
598422, 7980452, 8145105, 10047893, 14797229, 29204524, 44424807, 46507493, 49681219, 50077764, 56480783, 57309160, 80217992, 83100521, 87623901, 92308761, 92310322, 103401549, 104014717, 104179003, 111635622, 117498515, 126609105, 127305362, 127305363, 127305364, 127305365, 127305366, 127305367, 127305368, 127305369, 127305370, 128520104, 128520105, 134973208, 135231014, 135652709, 136076620, 136202233, 136904085, 137019039, 137224223, 139072192, 142847474, 152164544, 152248148, 160846349, 162178599, 162202314, 162224671
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ChEBI ID |
ChEBI:15854
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SuperDrug ATC ID |
P01BC01
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SuperDrug CAS ID |
cas=000056542
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Target and Pathway | |||||
Target(s) | E3 ubiquitin protein ligase COP1 | Target Info | Modulator | [556264] | |
KEGG Pathway | p53 signaling pathway | ||||
Ubiquitin mediated proteolysis | |||||
PANTHER Pathway | P53 pathway feedback loops 1 | ||||
References | |||||
Ref 538576 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 021799. | ||||
Ref 539633 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2510). |
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