Drug Information
Drug General Information | |||||
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Drug ID |
D03CHE
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Former ID |
DIB000811
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Drug Name |
PF-251802
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Synonyms |
PF-00251802; Selective glucocorticoid receptor agonist (1), Pfizer
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Indication | Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] | Discontinued in Phase 1 | [548806] | ||
Company |
Pfizer Inc
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Structure |
Download2D MOL |
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Canonical SMILES |
Cc1ncccc1NC(=O)c2ccc3c(CC[C@@H]4C[C@](O)(CC[C@@]34Cc5cc<br />ccc5)C(F)(F)F)c2
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InChI |
1S/C29H29F3N2O2/c1-19-25(8-5-15-33-19)34-26(35)22-10-12-24-21(16-22)9-11-23-18-28(36,29(30,31)32)14-13-27(23,24)17-20-6-3-2-4-7-20/h2-8,10,12,15-16,23,36H,9,11,13-14,17-18H2,1H3,(H,34,35)/t23-,27+,28-/m1/s1
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InChIKey |
QJJBNCHSWFGXML-KEKPKEOLSA-N
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Target and Pathway | |||||
Target(s) | Glucocorticoid receptor | Target Info | Agonist | [550632] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
TCR Signaling Pathway | |||||
References |
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