Drug General Information
Drug ID
D02XYB
Former ID
DIB002353
Drug Name
SARIPIDEM
Synonyms
SL-85.0274; Saripidem < Rec INN >; N-[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-ylmethyl]-N-methylbutanamide
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Phase 2 [525986]
Structure
Download
2D MOL

3D MOL

Formula
C19H20ClN3O
Canonical SMILES
CCCC(=O)N(C)Cc1c(nc2ccccn12)c3ccc(Cl)cc3
InChI
1S/C19H20ClN3O/c1-3-6-18(24)22(2)13-16-19(14-8-10-15(20)11-9-14)21-17-7-4-5-12-23(16)17/h4-5,7-12H,3,6,13H2,1-2H3
InChIKey
LIFDPEORUVTOCP-UHFFFAOYSA-N
CAS Number
CAS 103844-86-6
PubChem Compound ID
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [525986]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 525986Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue. Behav Pharmacol. 1995 Mar;6(2):116-126.
Ref 525986Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue. Behav Pharmacol. 1995 Mar;6(2):116-126.

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