Drug General Information
Drug ID
D02XSA
Former ID
DIB013227
Drug Name
Stiripentol
Synonyms
Diacomit; ME-2080; Stiripentol (oral); Stiripentol (oral), Laboratoires Biocodex
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Approved [528174], [540871]
Company
Laboratoires Biocodex
Structure
Download
2D MOL

3D MOL

Formula
C14H18O3
InChI
InChI=1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+
InChIKey
IBLNKMRFIPWSOY-FNORWQNLSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [528174], [551871]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 528174Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels. Epilepsia. 2006 Apr;47(4):704-16.
Ref 540871(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5469).
Ref 528174Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels. Epilepsia. 2006 Apr;47(4):704-16.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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