Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02WST
|
||||
| Former ID |
DIB009429
|
||||
| Drug Name |
Unfractionated heparin
|
||||
| Synonyms |
Elaprin; UFH (solid oral), Emisphere; Unfractionated heparin (solid oral, eligen); SNAC/heparin capsule (solid oral), Emisphere; SNAD/heparin tablet (solid oral), Emisphere; Unfractionated heparin (solid oral, eligen), Emisphere
|
||||
| Indication | Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Phase 3 | [1] | ||
| Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Phase 1 | [2] | |||
| Company |
Emisphere Technologies Inc
|
||||
| Target and Pathway | |||||
| Target(s) | Antithrombin-III | Target Info | Modulator | [3] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Pathway Interaction Database | Glypican 1 network | ||||
| Reactome | Intrinsic Pathway of Fibrin Clot Formation | ||||
| Common Pathway of Fibrin Clot Formation | |||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Formation of Fibrin Clot (Clotting Cascade) | |||||
| References | |||||
| REF 1 | Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: observations from the TIMI 8 trial. The Thrombolysis in Myocardial Infarction. Am Heart J. 2002 Feb;143(2):229-34. | ||||
| REF 2 | Clinical pipeline report, company report or official report of Emisphere Technologies. | ||||
| REF 3 | Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma. Thromb Res. 1982 Nov 15;28(4):487-97. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.