TTD | Drug: D02VIZ

Drug General Information
Drug ID	D02VIZ
Former ID	DIB019931
Drug Name	GR 196429
Synonyms	GR196429; GR-196429
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538826]
Structure		Download 2D MOL
Formula	C14H18N2O2
InChI	InChI=1S/C14H18N2O2/c1-10(17)15-6-8-16-7-4-11-2-3-13-12(14(11)16)5-9-18-13/h2-3H,4-9H2,1H3,(H,15,17)
InChIKey	LTYWTNUOUBBVNZ-UHFFFAOYSA-N
PubChem Compound ID	5311134
PubChem Substance ID	7979443, 11056293, 14774202, 39340851, 47285941, 47510149, 57359369, 76619069, 85220032, 114155352, 128541203, 135650316, 136351164, 137940991, 140376695, 179293784, 225016362, 227949278
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Agonist	[534642]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538826	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1349).
Ref 534642	GR196429: a nonindolic agonist at high-affinity melatonin receptors. J Pharmacol Exp Ther. 1998 Jun;285(3):1239-45.

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Drug Information