Drug Information
Drug General Information | |||||
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Drug ID |
D02RQT
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Former ID |
DNC014533
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Drug Name |
TENIDAP
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Drug Type |
Small molecular drug
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Indication | Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] | Phase 3 | [1], [2] | ||
Structure |
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Download2D MOL |
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Formula |
C14H9ClN2O3S
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InChI |
InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11-
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InChIKey |
LXIKEPCNDFVJKC-QXMHVHEDSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
7980752, 14718345, 14874738, 26683989, 26686056, 29216033, 31919866, 47207730, 50064246, 53789318, 88531322, 104829165, 135028984, 135651243, 135698204, 137231438, 143388439, 160671983, 164150758, 164814894, 172914502, 179149455, 179294229, 198938260, 198993721, 204359548, 226413131, 227840142, 252156629, 252356965
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SuperDrug ATC ID |
M01AX23
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Target and Pathway | |||||
Target(s) | Arachidonate 5-lipoxygenase | Target Info | Modulator | [1] | |
BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
Resolvin D biosynthesis | |||||
Leukotriene biosynthesis | |||||
Lipoxin biosynthesis | |||||
Aspirin triggered resolvin D biosynthesis | |||||
Aspirin triggered resolvin E biosynthesis | |||||
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Toxoplasmosis | |||||
NetPath Pathway | IL4 Signaling Pathway | ||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
WikiPathways | Vitamin D Receptor Pathway | ||||
Arachidonic acid metabolism | |||||
Eicosanoid Synthesis | |||||
Selenium Micronutrient Network | |||||
References | |||||
REF 1 | The in vitro free radical scavenging activity of tenidap, a new dual cyclo-oxygenase and 5-1ipoxygenase inhibitor. Mediators Inflamm. 1992;1(2):141-3. | ||||
REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2395). | ||||
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