Drug Information

Drug General Information
Drug ID
D02RIV
Former ID
DAP000850
Drug Name
Hydroxystilbamidine Isethionate
Synonyms
Hydroxystilbamide; Hydroxystilbamidine diisethionate; FluoroGold (TN); Ethanesulfonic acid, 2-hydroxy-, compd. with 2-hydroxy-4,4'-stilbenedicarboxamidine (2:1); Ethanesulfonic acid, 2-hydroxy-, compd. with 2-hydroxy-4,4'-stilbenedicarboxamidine (2:1) (8CI); Benzenecarboximidamide, 4-(2-(4-(aminoiminomethyl)phenyl)ethenyl)-3-hydroxy-, bis(2-hydroxyethanesulfonate) (salt); Ethanesulfonic acid, 2-hydroxy-, compd. with 4-(2-(4-(aminoiminomethyl)phenyl)ethenyl)-3-hydroxybenzenecarboximidamide (2:1); (4E)-4-[2-[4-(diaminomethylidene)cyclohexa-2,5-dien-1-ylidene]ethylidene]-3-oxocyclohexa-1,5-diene-1-carboximidamide; 2-Hydroxy-4,4'-diamidinostilbene di(beta-hydroxyethanesulfonate); 2-Hydroxy-4,4'-diguanylstilbene diisethionate; 2-Hydroxy-4,4'-stilbenedicarboxamidine bis(2-hydroxyethanesulfonate) (salt); 2-Hydroxy-4,4'-stilbenedicarboxamidine diisethionate; 2-Hydroxyethanesulphonic acid, compoundwith 4-(2-(4-amidinophenyl)vinyl)-3-hydroxybenzenecarboxamidine (2:1); 2-Hydroxystilbamidine diisethionate; 2-Hydroxystilbamidine isethionate; 2-hydroxyethanesulfonic acid
Drug Type
Small molecular drug
Indication Blastomycosis [ICD9: 116; ICD10:B40] Approved [538413]
Therapeutic Class
Antifungal Agents
Structure
Download
2D MOL

3D MOL
Formula
C20H28N4O9S2
Canonical SMILES
C1=CC(=C(N)N)C=CC1=CC=C2C=CC(=CC2=O)C(=N)N.C(CS(=O)(=O)<br />O)O.C(CS(=O)(=O)O)O
InChI
1S/C16H16N4O.2C2H6O4S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*3-1-2-7(4,5)6/h1-9H,17-18H2,(H3,19,20);2*3H,1-2H2,(H,4,5,6)/b11-4+;;
InChIKey
VIDDZUWWPMDEHU-QKBHCULISA-N
CAS Number
CAS 533-22-2
PubChem Compound ID
5359440
PubChem Substance ID
39383777, 50064871, 57361924, 78553817, 114147500, 134977035
Target and Pathway
Target(s) Bacterial DNA Target Info Modulator
References
Ref 538413FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 009166.

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