Drug General Information
Drug ID	D02MVG
Former ID	DIB010154
Drug Name	AMG-548
Synonyms	P38 MAP kinase inhibitor, Amgen
Drug Type	Small molecular drug
Indication	Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25]		Terminated	[547846]
Company	Amgen Inc
Structure		Download 2D MOL 3D MOL
Formula	C29H27N5O
Canonical SMILES	c1cc2c(cc1)cc(cc2)c1c(nc(n(c1=O)C)NC[C@H](Cc1ccccc1)N)c<br />1ccncc1
PubChem Compound ID	11167112
Target and Pathway
Target(s)	Stress kinase p38	Target Info	Inhibitor	[527639]
References
Ref 547846	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019881)
Ref 527639	p38 MAP kinase inhibitors: many are made, but few are chosen. Curr Opin Drug Discov Devel. 2005 Jul;8(4):421-30.

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