Drug General Information
Drug ID	D02JWY
Former ID	DNC014157
Drug Name	SRI-224
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530419]
Structure		Download 2D MOL 3D MOL
Formula	C10H13N3OS
Canonical SMILES	CC(=NNC(=S)N)C1=CC=C(C=C1)OC
InChI	1S/C10H13N3OS/c1-7(12-13-10(11)15)8-3-5-9(14-2)6-4-8/h3-6H,1-2H3,(H3,11,13,15)/b12-7+
InChIKey	JPXKIPVPEBSPLT-KPKJPENVSA-N
PubChem Compound ID	9561005
Target and Pathway
Target(s)	Tyrosine oxidase	Target Info	Inhibitor	[530419]
BioCyc Pathway	(S)-reticuline biosynthesis
	Eumelanin biosynthesis
	L-dopachrome biosynthesis
KEGG Pathway	Tyrosine metabolism
	Riboflavin metabolism
	Metabolic pathways
	Melanogenesis
PathWhiz Pathway	Riboflavin Metabolism
	Tyrosine Metabolism
WikiPathways	Dopamine metabolism
References
Ref 530419	Bioorg Med Chem Lett. 2009 Nov 1;19(21):6157-60. Epub 2009 Sep 10.Discovery of 4-functionalized phenyl-O-beta-D-glycosides as a new class of mushroom tyrosinase inhibitors.
Ref 530419	Bioorg Med Chem Lett. 2009 Nov 1;19(21):6157-60. Epub 2009 Sep 10.Discovery of 4-functionalized phenyl-O-beta-D-glycosides as a new class of mushroom tyrosinase inhibitors.

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