Drug General Information
Drug ID
D02HSB
Former ID
DCL000502
Drug Name
Cabazitaxel
Synonyms
Jevtana; Taxoid XRP6258; Jevtana (TN)
Drug Type
Small molecular drug
Indication Breast cancer; Prostate cancer [ICD9: 174, 175, 185; ICD10:C50, C61] Approved [531351], [541879]
Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [531351], [541879]
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL

Formula
C45H57NO14
InChI
InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
InChIKey
BMQGVNUXMIRLCK-OAGWZNDDSA-N
CAS Number
CAS 890654-44-1
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
L01CD04
Target and Pathway
Target(s) Tubulin Target Info Inhibitor [531351]
References
Ref 531351Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
Ref 541879(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6798).
Ref 531351Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.

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