Drug Information
Drug General Information | |||||
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Drug ID |
D02EYG
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Former ID |
DCL000553
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Drug Name |
Linagliptin
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Synonyms |
Ondero; BI 1356; BI-1356; Ondero (TN); BI-1356-BS; (R)-8-(3-Amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione
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Drug Type |
Small molecular drug
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Company |
Boehringer Ingelheim
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Structure |
Download2D MOL |
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Formula |
C25H28N8O2
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InChI |
InChI=1S/C25H28N8O2/c1-4-5-13-32-21-22(29-24(32)31-12-8-9-17(26)14-31)30(3)25(35)33(23(21)34)15-20-27-16(2)18-10-6-7-11-19(18)28-20/h6-7,10-11,17H,8-9,12-15,26H2,1-3H3/t17-/m1/s1
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InChIKey |
LTXREWYXXSTFRX-QGZVFWFLSA-N
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CAS Number |
CAS 668270-12-0
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PubChem Compound ID | |||||
PubChem Substance ID |
15083733, 22505980, 29196126, 39156222, 56310616, 80795936, 103537922, 104097872, 124490306, 124772145, 126626882, 126665800, 134345106, 135257632, 135693249, 136367897, 137171672, 141692239, 144116143, 152090598, 152134670, 152159563, 152258162, 160644541, 160645740, 160646999, 162011748, 162198501, 164020949, 164193945, 164228213, 164761585, 172653134, 174006340, 174530256, 175267212, 175427132, 178102936, 184817874, 198992878, 223377286, 223554902, 223678280, 223704799, 226523537, 241125887, 242588098, 249072929, 249737177, 251971307
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SuperDrug ATC ID |
A10BH05
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Target and Pathway | |||||
Target(s) | Dipeptidyl peptidase IV | Target Info | Inhibitor | [537022], [550386] | |
KEGG Pathway | Protein digestion and absorption | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
TGF_beta_Receptor Signaling Pathway | |||||
References | |||||
Ref 541464 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6318). | ||||
Ref 551882 | Clinical pipeline report, company report or official report of Boehringer Ingelheim. |
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