Drug Information
Drug General Information | |||||
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Drug ID |
D02DFT
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Former ID |
DNC006298
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Drug Name |
4-(5-(4-(methylamino)phenyl)thiophen-2-yl)phenol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [527907] | ||
Structure |
Download2D MOL |
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Formula |
C17H15NOS
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Canonical SMILES |
CNC1=CC=C(C=C1)C2=CC=C(S2)C3=CC=C(C=C3)O
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InChI |
1S/C17H15NOS/c1-18-14-6-2-12(3-7-14)16-10-11-17(20-16)13-4-8-15(19)9-5-13/h2-11,18-19H,1H3
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InChIKey |
CXLILFMFVYDZLM-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527907] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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